Targeted, minimally invasive treatment for pre-cancers, sun damage, and acne.

Photodynamic Therapy (PDT), also known as Blue Light Therapy, is an advanced treatment that uses a photosensitizing agent and a specific wavelength of light to selectively destroy abnormal or precancerous skin cells while leaving surrounding healthy tissue intact. It is FDA-approved for actinic keratoses (pre-cancers) and widely used for sun-damaged skin, superficial skin cancers, and acne. PDT is particularly valuable for treating large areas of sun-damaged skin with minimal scarring and excellent cosmetic results — avoiding the need for surgery in many cases.

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Conditions Treated with PDT

  • Actinic keratoses (pre-cancers) — the most common indication
  • Sun-damaged skin and field cancerization (large areas of extensive sun damage)
  • Superficial basal cell carcinoma
  • Acne vulgaris (moderate to severe)
  • Photorejuvenation — overall skin texture and tone improvement
  • Bowen’s disease (squamous cell carcinoma in situ)
Photodynamic Therapy

Your PDT Treatment — Step by Step

1

Skin Preparation

The treatment area is thoroughly cleansed, and the photosensitizing
agent (5-ALA) is applied to the skin surface.

2

Incubation Period

The agent absorbs into the skin for a defined period, ensuring
selective uptake by precancerous and abnormal cells.

3

Light Activation

The treated area is exposed to blue or red light, activating the
photosensitizer to produce reactive oxygen species that destroy
targeted abnormal cells.

4

Recovery

Expect redness and sensitivity for a few days. Strict sun avoidance
is required for 48 hours after treatment. You may experience peeling
and crusting as abnormal cells shed — do not pick.

5

Follow-Up

A series of treatments may be recommended for optimal results.
Dr. Mann monitors your response and adjusts the plan accordingly.

PDT is performed as an outpatient procedure at our Hendersonville office — no surgery, no general anesthesia.

It avoids damaging the normal skin in the treatment area, providing better cosmetic outcomes compared to some surgical options, especially for large areas of sun-damaged skin.

Book a PDT Consultation Call (615) 266-3376

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